Biography
Mertens obtained her PhD in neuroscience at Vrije Universiteit Amsterdam (2025), within the Center for Neurogenomics and Cognitive Research (CNCR), with a thesis entitled ‘Human pyramidal neurons at the center of brain diversity’. In this research, she studied the structural and functional properties of brain cells in surgically obtained (living) human brain tissue. This resulted in a unique dataset, which she used to reveal differences between brain areas at the level of individual cells. Her work was characterized by the analysis of complex laboratory data, with a strong emphasis on methodological substantiation and statistical validation. After obtaining her PhD, she consciously chose a direction in which she could apply her analytical skills to socially relevant issues. She obtained her bachelor's degree in Health & Life Sciences and her research master's degree in Neurosciences, both from VU University Amsterdam, in 2017 and 2019, respectively.
International activities
Interests
Most relevant publications
- Mertens, E. J., Leibner, Y., Pie, J., Galakhova, A. A., Waleboer, F., Meijer, J., ... & de Kock, C. P. J. (2024).
Morpho-electric diversity of human hippocampal CA1 pyramidal neurons. Cell Reports, 43(4), 114100. - Hunt, S., Leibner, Y., Mertens, E. J., Barros-Zulaica, N., Kanari, L., Heistek, T. S., ... & de Kock, C. P. J. (2023).
Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex. Cerebral Cortex, 33(6), 2857–2878.
Berg, J., Sorensen, S. A., Ting, J. T., Miller, J. A., Chartrand, T., Buchin, A., ... & Lein, E. S. (2021). - Human neocortical expansion involves glutamatergic neuron diversification. Nature, 598(7879), 151–158.
- Wilbers, R., Metodieva, V. D., Duverdin, S., Heyer, D. B., Galakhova, A. A., Mertens, E. J., ... & Goriounova, N. A. (2023).
Human voltage-gated Na⁺ and K⁺ channel properties underlie sustained fast AP signaling. Science Advances, 9(41), eade3300. - Wilbers, R., Galakhova, A. A., Driessens, S. L. W., Heistek, T. S., Metodieva, V. D., Hagemann, J., ... & Goriounova, N. A. (2023).
Structural and functional specializations of human fast-spiking neurons support fast cortical signaling. Science Advances, 9(41), eadf0708.